Professor Pengxia Wang (South China University of Technology; recruited through a talent program in April 2025) is a PhD supervisor whose long-term research focuses on microbial mobile genomes. She has achieved multiple innovative outcomes across two major areas: fundamental research and synthetic biology technologies. In fundamental studies, she investigates the functions of mobile genetic elements, providing new strategies for the prevention and control of pathogenic Vibrio. On the technology-development front, she has led the development of novel large-fragment DNA transfer technologies and high-efficiency genome-editing tools, and has systematically mined non-model microbial resources to advance synthetic biology.
She has been selected as a member of the Chinese Academy of Sciences (CAS) Youth Innovation Promotion Association and a CAS “Distinguished Backbone” talent, and has received multiple talent honors, including the Hainan Provincial Outstanding Youth Science Foundation. She has served as principal investigator for a range of competitive research grants, including three National Natural Science Foundation of China (NSFC) projects (two General Program grants and one Young Scientists Fund), as well as the Fundamental Research Funds for the Central Universities, a Guangdong Provincial Natural Science Foundation General Program project, and a Guangzhou Science and Technology Program project. As first or corresponding author (including co-first/co-corresponding author), she has published more than 30 papers in leading international journals such as Nature Ecology & Evolution, PNAS, The ISME Journal, and Environmental Microbiology, and holds two authorized invention patents. She currently serves on the editorial boards of Genes and Tropical Oceanography, and actively promotes academic exchange and disciplinary development.
September 2007 – June 2013: PhD, College of Life Science and Technology, Huazhong Agricultural University
September 2003 – July 2007: Bachelor’s degree, College of Life Sciences, Guizhou University
Synthetic Biology; Marine microorganisms; Horizontal gene transfer; Genome editing technologies.
Biotech pharmaceuticals; Marine Bioeconomy
- Yilong Ruan,Efficient genetic manipulation of Shewanella through targeting defense islands,Appl Environ Microbiol,2025.3.21
- Pengxia Wang, Xiaofei Du,Combining CRISPR/Cas9 and natural excision for the precise and complete removal of mobile genetic elements in bacteria,Appl Environ Microbiol,2024.03.18
- Tongxuan Cai,Genomic Island-Encoded Diguanylate Cyclase from Vibrio alginolyticus Regulates Biofilm Formation and Motility in Pseudoalteromonas,Microorganisms,2023.11.08
- Pengxia Wang, Weiquan Wang,Kaihao Tang,The coral pathogen Vibrio coralliilyticus kills non-pathogenic holobiont competitors by triggering prophage induction,Nat Ecol Evol,2022.06.30
- Penxia Wang,Mobile genetic elements used by competing coral microbial populations increase genomic plasticity,ISME J,2022.06.27
- Yi Zhao,The HipAB Toxin-Antitoxin System Stabilizes a Composite Genomic Island in Shewanella putrefaciens CN-32,Front Microbiol,2022.03.21
- Songwei Ni, Baiyuan Li ,Conjugative plasmid-encoded toxin-antitoxin system PrpT/PrpA directly controls plasmid copy number,Proc Natl Acad Sci U S A,2021.01.26
- Pengxia Wang,Eliminating mcr-1-harbouring plasmids in clinical isolates using the CRISPR/Cas9 system,J Antimicrob Chemother,2019.12.01
- Pengxia Wang,Dissemination and loss of a biofilm-related genomic island in marine Pseudoalteromonas mediated by integrative and conjugative elements,Environ Microbiol,2017.11.08
- Pengxia Wang, Zhongling Wen,Interaction of type IV toxin/antitoxin systems in cryptic prophages of Escherichia coli K-12,Toxins,2017.03.1
- Pengxia Wang,Mob/oriT, a mobilizable site-specific recombination system for unmarked genetic manipulation in Bacillus thuringiensis and Bacillus cereus,Microb Cell Fact,2016.06.10
- Pengxia Wang,Development of an efficient conjugation-based genetic manipulation system for Pseudoalteromonas,Microb Cell Fact,2015.01.23
- Pengxia Wang,The resolution and regeneration of a cointegrate plasmid reveals a model for plasmid evolution mediated by conjugation and oriT site-specific recombination,Environ Microbiol,2013.07.04