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Shipeng

Professor,

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Department: School of Biomedical Science and Engineering

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Biography

Dr. Peng Shi, Professor, recipient of the National Excellent Young Scientists Fund, and Principal Investigator of the National Key R&D Program Youth Project.

 

He obtained his Ph.D. from the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, in 2016. From 2016 to 2020, he conducted postdoctoral research in the Department of Biomedical Engineering at Pennsylvania State University, USA. In September 2020, he joined the School of Biomedical Sciences and Engineering at South China University of Technology as a professor and Ph.D. supervisor. Professor Shi is dedicated to developing chemical modification-based cell engineering technologies. As the corresponding author, he has published 20 papers in internationally renowned academic journals such as Sci Adv, Nat Commun, Angew Chem Int Ed, Adv Mater. He has led several research projects, including the National Key R&D Program Youth Project, the National Excellent Young Scientists Fund, and the National Natural Science Foundation of China General Program. He also serves as a youth editorial board member for Exploration and Chinese Chemical Letters.


Education

2010-09~2016-01, University of the Chinese Academy of Sciences, Chemistry, PhD;

2006-09~2010-07, Inner Mongolia University, Applied Chemistry, Bachelor's.

Admission Information

WorkExperience

2020-09~now, South China University of Technology, Professor

2016-04~2020-07, Pennsylvania State University, Postdoctoral Fellow


Social Position

Research Areas

Cell engineering; biomolecular self-assembly, biomaterial self-assembly;


Main research directions:

(1) Polymerization in living cells for cell engineering and cell function regulation.

(2) Cell surface modification with biomacromolecules and natural polymers for cell function regulation.

(3) Biomedical applications of engineered cells: improving cell homing, increasing transplanted cell survival, and enhancing cell therapy function


Courses Taught

Frontiers in Chemical Biology;

Biomaterials Surface and Engineering;

Comprehensive Biomedical Experiments;

Advanced Biomaterials Technology.


Research Project

National Key R&D Program Youth Project; 

National Excellent Young Scientists Fund; 

National Natural Science Foundation of China - General Program;

Guangdong Natural Science Foundation of China - General Program;

Fundamental Research Funds for Central University.

Selected Publications

  • Zhong, Xianghua; Luo, Li; Wu, Jiyuan; Li, Weirun; Liu, Xinyang; Ye, Tenghui; Li, Zhenhua; Shi, Peng ,Adhesion-Assisted Antioxidant-Engineered Mesenchymal Stromal Cells for Enhanced Cardiac Repair in Myocardial Infarction,ACS Nano,2025
  • Ye, Tenghui; Wu, Zixin; Liu, Xi; Wu, Jiyuan; Fu, Qin; Cao, Jie; Zhang, Di; Shi, Peng ,Engineered mesenchymal stromal cells with bispecific polyvalent peptides suppress excessive neutrophil infiltration and boost therapy,Science Advances,2025
  • Liu, Xi; Ye, Tenghui; Yang, Leyi; Wu, Jiamin; Fu, Qin; Peng, Xi; Luo, Jiajia; Huang, Xiaobo; Zhang, Di; Shi, Peng ,DNA-Scaffolded Bispecific Antibodies Enhance Mesenchymal Stromal Cell Therapy for Inflammatory Bowel Disease,Advanced Materials,2025
  • Lv, Yuheng;Fu, Qin;Xu, Yi;Shi, Peng,Sequentially-Activated Antibodies Based on Programmable DNA Tags for Rapid Multiplexed Protein Imaging,Small,2024
  • Ye, Tenghui;Liu, Xi;Zhong, Xianghua;Yan, Ran;Shi, Peng,Nongenetic surface engineering of mesenchymal stromal cells with polyvalent antibodies to enhance targeting efficiency,Nature Communications,2023

Achievements

Patent

  • 石鹏;钟祥华,一种基于聚多巴胺和VCAM1抗体的干细胞工程化改造方法及其应用,2024107837519,2025-08-19
  • 石鹏;刘鑫超,一种用于间充质干细胞封装的自组装聚合物材料及其制备方法与应用,2024104971709,2025-04-08
  • 石鹏;叶腾辉;钟祥华;晏然;刘茜,一种基于蛋白多聚体的间充质干细胞工程化改造方法及其应用,2023100022086,2023-09-26
  • 石鹏;钟祥华,一种基于聚多巴胺和VCAM1 抗体的干细胞工程化改造方法及其应用,PCT/CN2024/111773,/
  • 石鹏;刘鑫超,一种用于间充质干细胞封装的自组装聚合物材料及其制备方法与应用,PCT/CN2024/111775,/
  • 石鹏;吕宇恒,一种快速实现多通路免疫荧光成像的DNA标签及其应用,202310547704X

Honor

Software achievement