头像

Zhangchunyu

Professor,

Tel:

Email:

Department:

Office Location:

Search:

About

Education

Admission Information

WorkExperience

Social Position

Research

Open Course

Research Project

Thesis

  • Sun, Luyao;Ke, Miaola;Yin, Mengyuan;Zeng, Ying;Ji, Yutong;Hu, Yiming;Fu, Songbin;Zhang, Chunyu,Extracellular vesicle-encapsulated microRNA-296-3p from cancer-associated fibroblasts promotes ovarian cancer development through regulation of the PTEN/AKT and SOCS6/STAT3 pathways,CANCER SCIENCE,115
  • 尹梦媛;孙路遥;张春玉,免疫调节因子miR-433-3p通过靶向MAPK8及GRB2调控卵巢癌进展的机制研究,国际免疫学杂志,46
  • Sun, Luyao;Ke, Miaola;Wang, Xin;Yin, Mengyuan;Wei, Junni;Xu, Lu;Tian, Xing;Wang, Fei;Zhang, He;Fu, Songbin;Zhang, Chunyu,FAPhigh α-SMAlow cancer-associated fibroblast-derived SLPI protein encapsulated in extracellular vesicles promotes ovarian cancer development via activation of PI3K/AKT and downstream signaling pathways,Molecular Carcinogenesis,61
  • Yuan, Feifei;Wang, Zhijuan;Sun, Yanli;Wei, Hongwei;Cui, Yanying;Wu, Zhanying;Zhang, Chunyu;Xie, Ke-Ping;Wang, Fengchao;Zhang, Meijia,Sgpl1 deletion elevates S1P levels, contributing to NPR2 inactivity and p21 expression that block germ cell development,Cell Death & Disease,12
  • 刘雨蒙;孙路遥;张春玉,肿瘤相关成纤维细胞调控肿瘤免疫反应的研究进展,国际遗传学杂志,44
  • Yu, Sen;Zhang, Chunyu;Xie, Ke-Ping,Therapeutic resistance of pancreatic cancer: Roadmap to its reversal,Biochimica et Biophysica Acta-Reviews on Cancer,1875
  • 孙路遥;尹梦媛;谢克平;张春玉,肿瘤相关成纤维细胞在胰腺癌发生发展中的研究进展,肿瘤学杂志,27
  • 张春玉,肿瘤微环境中细胞融合机制的研究进展.
  • Li, Jia;Zhang, Yu;Zheng, Nana;Li, Biao;Yang, Jing;Zhang, Chunyu;Xia, Guoliang;Zhang, Meijia,CREB activity is required for mTORC1 signaling-induced primordial follicle activation in mice,Histochemistry and Cell Biology,154
  • 张春玉,Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells.
  • 张春玉,外泌体及其在卵巢癌中的研究进展.
  • 张春玉,Sei-1 can promote the formation of double minute chromosomes through activation of the PI3K/Akt/BRCA1-Abraxas pathway and inducing double-strand breaks in NIH-3T3 murine fibroblasts.
  • 张春玉,SEI1 induces genomic instability by inhibiting DNA damage response in human ovarian cancer.
  • 张春玉,数字PCR概述
  • 张春玉,Met promotes the formation of double minute chromosomes induced by Sei-1 in NIH-3T3 murine fibroblasts.
  • 张春玉,肿瘤相关成纤维细胞在卵巢癌中的研究进展
  • 张春玉,基因编辑技术的研究进展
  • 张春玉,Ribosomal L22-like1 (RPL22L1) Promotes Ovarian Cancer Metastasis by Inducing Epithelial-to-Mesenchymal Transition.
  • 张春玉,Constitutive ERK1/2 activation contributes to production of double minute chromosomes in tumour cells.
  • 张春玉,Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells.
  • 张春玉,De novo-generated small palindromes are characteristic of amplicon boundary junction of double minutes.
  • 张春玉,Gemcitabine Eliminates Double Minute Chromosomes from Human Ovarian Cancer Cells.
  • 张春玉,肿瘤相关性成纤维细胞与肿瘤关系的初探.
  • 张春玉,TNF-α,IL-10在变应性鼻炎中的作用研究
  • 张春玉,Wnt2 Secreted by Tumor Fibroblasts Promotes Tumor Growth in Esophageal Cancer via the activation of Wnt/β-catenin signaling pathway.
  • 张春玉,haracterization of a novel mechanism of genomic instability involving the SEI1/SET/NM23H1 pathway in esophageal cancers.
  • 张春玉,Comparative proteomic analysis of the esophageal squamous carcinoma cell line EC109 and its multi-drug resistant subline EC109/CDDP.
  • 张春玉,Fibroblast Growth Factor Receptor 2–Positive Fibroblasts Provide a Suitable Microenvironment for Tumor Development.

Achievements

  • 《医学遗传学》(规划教材),北医出版社,2024年1月
  • 《医学遗传学》英文改编版,科学出版社,2020年3月
  • 《临床遗传学》(规划教材),人卫出版社,2018年1月
  • SMITH人类先天性畸形图谱(第六版,人卫出版社,2007年5月
  • 医学遗传学实验指导(规划教材),北医出版社,2004年1月

Patent

Honor

  • “教师教学荣誉体系”教学优秀奖(本科),医学院(生命科学研究院),张春玉,2023
  • 教育部新世纪优秀人才,教育部,张春玉,2013年,省部级

Software achievement