个人简介
教育经历
- 1997-09~2000-06,华南理工大学,发酵工程,博士
- 1994-09~1997-07,华南农业大学
- 1990-09~1994-07,湖北农学院（现名为长江大学）
招生信息
- 专业学位硕导,生物科学与工程学院,086000,生物与医药,生物工程
- 专业学位硕导,生物科学与工程学院,105500,药学
- 学术型博导,生物科学与工程学院,071000,生物学,生物化学与分子生物学
- 学术型博导,生物科学与工程学院,082203,发酵工程
- 学术型硕导,生物科学与工程学院,082203,发酵工程
- 学术型硕导,生物科学与工程学院,071000,生物学,生物化学与分子生物学
工作经历
- 2000-07,华南理工大学
- 2000-07,华南理工大学
社会、学会及学术兼职
研究领域
科研兴趣：
（1）重要功能蛋白质的表达及应用；
（2）病原微生物及有毒有害物质的快速检测；
（3）生物基化学品及生物能源的绿色制造。
开授课程
本科生教学：承担本科生专业基础课（56学时）“现代工业微生物学”，通选课“普通生物学”（32学时）
本科生导师制：担任8-12名本科生的本科生导师（每年级2-3人）
研究生教学：承担生物化学与分子生物学专业“细胞生物学实验技术”
科研项目
（1）广东省基础与应用基础研究重大项目（2020B0301030005）：大宗食品中高污染致病性蜡样芽孢杆菌危害形成与防控分子机制，2020.11-2025.11，440万元，课题负责人，在研
（2）广州市重点研发计划（202103030003）：多功能组织工程支架的仿生制备关键技术及其在组织再生修复中的应用，2021.04-2024.03，150万元，课题负责人，在研，
（3）国家自然科学基金面上项目（21878103）：嗜热厌氧杆菌中精氨酸阻遏蛋白（ArgR）调控木糖代谢的机制研究，2019.01-2022.12，78万元，在研，主持
（4）国家自然科学基金面上项目（21676098）：嗜热厌氧杆菌葡萄糖木糖共利用的分子机制研究，2017.01-2020.12，90万元，在研，主持
（5）广东省省级科技计划项目（2019A050510008）：廉价生物质高效转化丁酸的底盘细胞构建及发酵工艺研究，2020.01-2021.12，50万，在研，主持
（6）国家自然科学基金面上项目（21276093）：嗜热厌氧杆菌在纤维床生物反应器中乙醇耐受性增强的分子机制研究，2013.01-2016.12，83万，已结题，主持
（7）中央高校基本科研业务费（2017PY013）：基于转录组学的嗜热厌氧杆菌木糖高效利用研究，2017.01-2018.12，15万，已结题，主持
（8）制浆造纸工程国家重点实验室开放基金（2017C03）：酪丁酸梭菌发酵廉价底物产丁酸的研究，2017.01-2018.12，10万，在研，主持
（9）广东省科技计划项目（国际合作）（2015A030310322）：厌氧发酵廉价生物质高效产丁醇的关键技术及工艺研究，2015.04-2017.03，50万，已结题，主持
论文
- Li, Yang;Liu, Mingxiong;Yang, Changyang;Fu, Hongxin;Wang, Jufang*,Engineering microbial metabolic homeostasis for chemicals production,Critical Reviews in Biotechnology,2025
- Fu, Hongxin*;Li, Xin;Guo, Xiaolong;Yang, Die;Nan, Chenchen;Cheng, Jiale;Du, Haoming;Shen, Mengju;Wang, Jufang*,Consolidated bioprocessing of cassava starch into butyric acid and butanol by engineered Clostridium butyricum SCUT 620,Bioresource Technology,2025
- Wang, Wenhai;Minami, Tsuyoshi;Sheng, Yixiao;Luo, Lun;Ma, Yi;Kang, Keren;Wang, Jufang*,Intelligent quantitative recognition of SARS-CoV-2 using machine learning-based ratiometric fluorescent paper sensors of metal-organic framework Al3+/Au NCs@ZIF-90,Chemical Engineering Journal,2025
- Ye, Fating;Feng, Jun;Guo, Xiaolong;Cheng, Jiale;Fu, Hongxin;Wang, Jufang*,Development of iterative genome-editing method based on a Rock-Paper-Scissors strategy in Clostridium tyrobutyricum for butyl butyrate from lignocellulosic biomass hydrolysate,Chemical Engineering Journal,2025
- Li, Yang;Liu, Mingxiong;Yang, Changyang;Zheng, Yujia;Xu, Guiping;Fu, Hongxin;Wang, Jufang*,Engineering Temperature-Powered Synthetic Multilayer Molecular Bioswitch for High-Level Pyruvate Derivative Production in Escherichia coli,ACS Synthetic Biology,2025
- Shan, Junzhuo;Sheng, Yixiao;Luo, Lun;Wang, Wenhai;Liu, Xinjiang;Ma, Yi;Wang, Jufang*,One-Pot Rlock-Mediated CRISPR/Cas12a-Driven RCA Cycle for Rapid and High-Sensitive APE1 Detection,Analytical Chemistry,2025
- Hong, Bin;Wang, Wenhai;Li, Yanmei;Ma, Yi*;Wang, Jufang*,Specific separation and sensitive detection of foodborne pathogens by phage-derived bacterial-binding protein-nano magnetic beads coupled with smartphone-assisted paper sensor,Biosensors and Bioelectronics,2024
- Guo, Xiaolong;Li, Xin;Feng, Jun;Yue, Zhi;Fu, Hongxin*;Wang, Jufang*;Guo Xiaolong;Li Xin;Feng Jun;Yue Zhi;Fu Hongxin*;Wang Jufang,Engineering of Clostridium tyrobutyricum for butyric acid and butyl butyrate production from cassava starch,Bioresource Technology,2024
- Dai, Kaiqun;Qu, Chunyun;Li, Xin;Lan, Yang;Fu, Hongxin*;Wang, Jufang*,Cofactor engineering in Thermoanaerobacterium aotearoense SCUT27 for maximizing ethanol yield and revealing an enzyme complex with high ferredoxin-NAD + reductase activity,Bioresource Technology,2024
- Guo, Xiaolong;Ye, Fating;Nan, Chenchen;Cheng, Jiale;Feng, Jun;Fu, Hongxin*;Wang, Jufang,Efficient production of butyl butyrate from mannitol by engineered Clostridium tyrobutyricum,Chemical Engineering Journal,2024
- Wang, Wenhai;Luo, Lun;Li, Yanmei;Hong, Bin;Ma, Yi;Kang, Keren;Wang, Jufang*,Detection of SARS-CoV-2 using machine learning-enabled paper-assisted ratiometric fluorescent sensors based on target-induced magnetic DNAzyme,Biosensors and Bioelectronics,2024
- Li, Yanmei;Hong, Bin;Luo, Lun;Wang, Wenhai;Ma, Yi;Wang, Jufang*;Li Yanmei;Hong Bin;Luo Lun;Wang Wenhai;Ma Yi;Wang Jufang*,Antimicrobial activity of magnolol against Bacillus cereus and its application as food preservative,Innovative Food Science & Emerging Technologies,2024
- Li, Yanmei;Luo, Lun;Wang, Wenhai;Hong, Bin;Ma, Yi;Wang, Jufang*,Synergistic antibacterial activity of cell wall hydrolase Lys14579 combined with cinnamaldehyde against emetic Bacillus cereus and their application in foods,Food Control,2024
- Dai, Kaiqun;Miao, Yuanhao;Qu, Chunyun;Wang, Cheng;Fu, Hongxin*;Wang, Jufang*,Adaptive laboratory evolution of Thermoanaerobacterium aotearoense for enhanced ethanol production from raw cassava starch,Renewable Energy,2024
- Song, Liu;Wang, Dianbing;Abbas, Ghulam;Li, Min;Cui, Mengmeng;Wang, Jufang;Lin, Zhanglin;Zhang, Xian-En,The main protease of SARS-CoV-2 cleaves histone deacetylases and DCP1A, attenuating the immune defense of the interferon-stimulated genes,JOURNAL OF BIOLOGICAL CHEMISTRY,2023
- Qin, Ting;Wang, Meng;Wu, Peidian;Zhang, Qiankun;Kang, Keren;Ma, Yi;Lin, Zhanglin;Wang, Jufang,Escherichia coli surface-displayed by Sup35NM nanofibrils and Z-domains fusion protein for signal enhancement in a biolayer interferometry-based immunoassay,Sensors and Actuators B: Chemical,2023
- Song Liu;Wang Dianbing;Abbas Ghulam;Li Min;Cui Mengmeng;Wang Jufang;Lin Zhanglin;Zhang XianEn,The main protease of SARS-CoV-2 cleaves histone deacetylases and DCP1A, attenuating the immune defense of the interferon-stimulated genes.,The Journal of biological chemistry,2023
- Guo, Xiaolong;Zhang, Huihui;Feng, Jun;Yang, Lu;Luo, Kui;Fu, Hongxin;Wang, Jufang,De novo biosynthesis of butyl butyrate in engineered Clostridium tyrobutyricum,Metabolic Engineering,2023
- Guo Xiaolong;Li Xin;Feng Jun;Yue Zhi;Fu Hongxin;Wang Jufang,Engineering of Clostridium tyrobutyricum for butyric acid and butyl butyrate production from cassava starch.,Bioresource technology,2023
- Li Jiaxuan;Li Yang;Li Yanmei;Ma Yi;Xu Wei;Wang Jufang,An enhanced activity and thermostability of chimeric Bst DNA polymerase for isothermal amplification applications.,Applied microbiology and biotechnology,2023
- Qu, Chunyun;Dai, Kaiqun;Liu, Gongliang*;Wang, Jufang*;Qu Chunyun;Dai Kaiqun;Liu Gongliang*;Wang Jufang*,Engineering Thermoanaerobacterium aotearoense SCUT27 with the deficiency of a hypothetic protein regulated by ArgR1864 for enhanced ethanol production from lignocellulosic hydrolysates,Renewable Energy,2023
- Dai, Kaiqun;Qu, Chunyun;Feng, Jun;Lan, Yang;Fu, Hongxin*;Wang, Jufang*;Dai Kaiqun;Qu Chunyun;Feng Jun;Lan Yang;Fu Hongxin;Wang Jufang,Metabolic engineering of Thermoanaerobacterium aotearoense strain SCUT27 for biofuels production from sucrose and molasses,Biotechnology for Biofuels and Bioproducts,2023
- Qin, Pengfei; Chen, Huaxian; Wang, Yuhang; Huang, Liang; Huang, Ke; Xiao, Guozhong; Han, Changpeng; Hu, Jiancong; Lin, Dezheng; Wan, Xingyang; Zheng, Yihui; Liu, Yufeng; Li, Guiming; Yang, Haojie; Ye, Shubiao; Luo, Minyi; Fu, Yuanji; Xu, Hao; Wen, Luping; Guo, Zhiwei,Cancer-associated fibroblasts undergoing neoadjuvant chemotherapy suppress rectal cancer revealed by single-cell and spatial transcriptomics,Cell Reports Medicine,2023
- Feng, Jun;Guo, Xiaolong;Cai, Feifei;Fu, Hongxin;Wang, Jufang,Model-based driving mechanism analysis for butyric acid production in Clostridium tyrobutyricum,Biotechnology for Biofuels and Bioproducts,2022
- Fu, Hongxin;Zhang, Huihui;Guo, Xiaolong;Yang, Lu;Wang, Jufang*,Elimination of carbon catabolite repression in Clostridium tyrobutyricum for enhanced butyric acid production from lignocellulosic hydrolysates,Bioresource Technology,2022
- Fu, Hongxin;Yue, Zhi;Feng, Jun;Bao, Teng;Yang, Shang-Tian;Cai, Youhua;Wang, Jufang,Consolidated bioprocessing for butyric acid production from raw cassava starch by a newly isolated Clostridium butyricum SCUT620,Industrial Crops and Products,2022
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获奖、荣誉称号
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