Prof. Wang is dedicated to the green manufacturing of functionally important proteins—including collagen, mussel-adhesive proteins and antimicrobial peptides—and of bio-based chemicals such as short-chain fatty acids/esters. She has also developed a series of paper-based sensors for the rapid detection of pathogenic microorganisms and toxic or hazardous substances. As first or corresponding author she has published nearly 170 papers in journals such as Cell Reports Medicine, Journal of the American Chemical Society and Biotechnology Advances, and her work has been cited almost 8,000 times to date. She holds 47 granted Chinese invention patents, has received four provincial or municipal science-and-technology awards, and, as principal investigator, has led more than 50 research projects—including the National 863 Key Programme, National Natural Science Foundation of China and Guangdong Provincial Major S&T Special Projects.
Dec. 2009--- Present: Professor, Department of Biotechnology, School of Bioscience and Bioengineering, South China University of Technology (SCUT)
Aug. 2013—Feb. 2014: The Ohio State University, visiting scholar, financial supported by The China Scholarship Council (CSC)
Sept. 2005--- Sept. 2006: Massachusettes Institute of Technology, visiting scholar, financial supported by The China Scholarship Council (CSC)
Sept. 1997-----Jun. 2000:South China University of Technology; PhD degree in fermentation. Guangzhou, China
Sept. 1994-----Jun. 1997: South China Agricultural University; MS degree in Pomology. Guangzhou, China,
Sept. 1990-----Jun. 1994: Yangtze University; BA degree in agronomy. Jingzhou, China
(1) Expression and application of important functional proteins; (2) Rapid detection of pathogenic microorganisms and toxic/harmful substances; (3) Green manufacturing of bio-based chemicals and biofuels.
Undergraduate degree:
Microbiology, Biopharmaceutical Technology, Bioethics, Biosafety and Modern Human Life,Integrated Biotechnology Experiments
Postgraduate degree:
Frontiers in Biochemistry and Molecular Biology, Cell Biology Laboratory Techniques
- Li, Yang;Liu, Mingxiong;Yang, Changyang;Fu, Hongxin;Wang, Jufang*,Engineering microbial metabolic homeostasis for chemicals production,Critical Reviews in Biotechnology,2025
- Fu, Hongxin*;Li, Xin;Guo, Xiaolong;Yang, Die;Nan, Chenchen;Cheng, Jiale;Du, Haoming;Shen, Mengju;Wang, Jufang*,Consolidated bioprocessing of cassava starch into butyric acid and butanol by engineered Clostridium butyricum SCUT 620,Bioresource Technology,2025
- Wang, Wenhai;Minami, Tsuyoshi;Sheng, Yixiao;Luo, Lun;Ma, Yi;Kang, Keren;Wang, Jufang*,Intelligent quantitative recognition of SARS-CoV-2 using machine learning-based ratiometric fluorescent paper sensors of metal-organic framework Al3+/Au NCs@ZIF-90,Chemical Engineering Journal,2025
- Ye, Fating;Feng, Jun;Guo, Xiaolong;Cheng, Jiale;Fu, Hongxin;Wang, Jufang*,Development of iterative genome-editing method based on a Rock-Paper-Scissors strategy in Clostridium tyrobutyricum for butyl butyrate from lignocellulosic biomass hydrolysate,Chemical Engineering Journal,2025
- Li, Yang;Liu, Mingxiong;Yang, Changyang;Zheng, Yujia;Xu, Guiping;Fu, Hongxin;Wang, Jufang*,Engineering Temperature-Powered Synthetic Multilayer Molecular Bioswitch for High-Level Pyruvate Derivative Production in Escherichia coli,ACS Synthetic Biology,2025
- Shan, Junzhuo;Sheng, Yixiao;Luo, Lun;Wang, Wenhai;Liu, Xinjiang;Ma, Yi;Wang, Jufang*,One-Pot Rlock-Mediated CRISPR/Cas12a-Driven RCA Cycle for Rapid and High-Sensitive APE1 Detection,Analytical Chemistry,2025
- Hong, Bin;Wang, Wenhai;Li, Yanmei;Ma, Yi*;Wang, Jufang*,Specific separation and sensitive detection of foodborne pathogens by phage-derived bacterial-binding protein-nano magnetic beads coupled with smartphone-assisted paper sensor,Biosensors and Bioelectronics,2024
- Guo, Xiaolong;Li, Xin;Feng, Jun;Yue, Zhi;Fu, Hongxin*;Wang, Jufang*;Guo Xiaolong;Li Xin;Feng Jun;Yue Zhi;Fu Hongxin*;Wang Jufang,Engineering of Clostridium tyrobutyricum for butyric acid and butyl butyrate production from cassava starch,Bioresource Technology,2024
- Dai, Kaiqun;Qu, Chunyun;Li, Xin;Lan, Yang;Fu, Hongxin*;Wang, Jufang*,Cofactor engineering in Thermoanaerobacterium aotearoense SCUT27 for maximizing ethanol yield and revealing an enzyme complex with high ferredoxin-NAD + reductase activity,Bioresource Technology,2024
- Guo, Xiaolong;Ye, Fating;Nan, Chenchen;Cheng, Jiale;Feng, Jun;Fu, Hongxin*;Wang, Jufang,Efficient production of butyl butyrate from mannitol by engineered Clostridium tyrobutyricum,Chemical Engineering Journal,2024
- Wang, Wenhai;Luo, Lun;Li, Yanmei;Hong, Bin;Ma, Yi;Kang, Keren;Wang, Jufang*,Detection of SARS-CoV-2 using machine learning-enabled paper-assisted ratiometric fluorescent sensors based on target-induced magnetic DNAzyme,Biosensors and Bioelectronics,2024
- Li, Yanmei;Hong, Bin;Luo, Lun;Wang, Wenhai;Ma, Yi;Wang, Jufang*;Li Yanmei;Hong Bin;Luo Lun;Wang Wenhai;Ma Yi;Wang Jufang*,Antimicrobial activity of magnolol against Bacillus cereus and its application as food preservative,Innovative Food Science & Emerging Technologies,2024
- Li, Yanmei;Luo, Lun;Wang, Wenhai;Hong, Bin;Ma, Yi;Wang, Jufang*,Synergistic antibacterial activity of cell wall hydrolase Lys14579 combined with cinnamaldehyde against emetic Bacillus cereus and their application in foods,Food Control,2024
- Dai, Kaiqun;Miao, Yuanhao;Qu, Chunyun;Wang, Cheng;Fu, Hongxin*;Wang, Jufang*,Adaptive laboratory evolution of Thermoanaerobacterium aotearoense for enhanced ethanol production from raw cassava starch,Renewable Energy,2024
- Song, Liu;Wang, Dianbing;Abbas, Ghulam;Li, Min;Cui, Mengmeng;Wang, Jufang;Lin, Zhanglin;Zhang, Xian-En,The main protease of SARS-CoV-2 cleaves histone deacetylases and DCP1A, attenuating the immune defense of the interferon-stimulated genes,JOURNAL OF BIOLOGICAL CHEMISTRY,2023
- Qin, Ting;Wang, Meng;Wu, Peidian;Zhang, Qiankun;Kang, Keren;Ma, Yi;Lin, Zhanglin;Wang, Jufang,Escherichia coli surface-displayed by Sup35NM nanofibrils and Z-domains fusion protein for signal enhancement in a biolayer interferometry-based immunoassay,Sensors and Actuators B: Chemical,2023
- Song Liu;Wang Dianbing;Abbas Ghulam;Li Min;Cui Mengmeng;Wang Jufang;Lin Zhanglin;Zhang XianEn,The main protease of SARS-CoV-2 cleaves histone deacetylases and DCP1A, attenuating the immune defense of the interferon-stimulated genes.,The Journal of biological chemistry,2023
- Guo, Xiaolong;Zhang, Huihui;Feng, Jun;Yang, Lu;Luo, Kui;Fu, Hongxin;Wang, Jufang,De novo biosynthesis of butyl butyrate in engineered Clostridium tyrobutyricum,Metabolic Engineering,2023
- Guo Xiaolong;Li Xin;Feng Jun;Yue Zhi;Fu Hongxin;Wang Jufang,Engineering of Clostridium tyrobutyricum for butyric acid and butyl butyrate production from cassava starch.,Bioresource technology,2023
- Li Jiaxuan;Li Yang;Li Yanmei;Ma Yi;Xu Wei;Wang Jufang,An enhanced activity and thermostability of chimeric Bst DNA polymerase for isothermal amplification applications.,Applied microbiology and biotechnology,2023
- Qu, Chunyun;Dai, Kaiqun;Liu, Gongliang*;Wang, Jufang*;Qu Chunyun;Dai Kaiqun;Liu Gongliang*;Wang Jufang*,Engineering Thermoanaerobacterium aotearoense SCUT27 with the deficiency of a hypothetic protein regulated by ArgR1864 for enhanced ethanol production from lignocellulosic hydrolysates,Renewable Energy,2023
- Dai, Kaiqun;Qu, Chunyun;Feng, Jun;Lan, Yang;Fu, Hongxin*;Wang, Jufang*;Dai Kaiqun;Qu Chunyun;Feng Jun;Lan Yang;Fu Hongxin;Wang Jufang,Metabolic engineering of Thermoanaerobacterium aotearoense strain SCUT27 for biofuels production from sucrose and molasses,Biotechnology for Biofuels and Bioproducts,2023
- Qin, Pengfei; Chen, Huaxian; Wang, Yuhang; Huang, Liang; Huang, Ke; Xiao, Guozhong; Han, Changpeng; Hu, Jiancong; Lin, Dezheng; Wan, Xingyang; Zheng, Yihui; Liu, Yufeng; Li, Guiming; Yang, Haojie; Ye, Shubiao; Luo, Minyi; Fu, Yuanji; Xu, Hao; Wen, Luping; Guo, Zhiwei,Cancer-associated fibroblasts undergoing neoadjuvant chemotherapy suppress rectal cancer revealed by single-cell and spatial transcriptomics,Cell Reports Medicine,2023
- Feng, Jun;Guo, Xiaolong;Cai, Feifei;Fu, Hongxin;Wang, Jufang,Model-based driving mechanism analysis for butyric acid production in Clostridium tyrobutyricum,Biotechnology for Biofuels and Bioproducts,2022
- Fu, Hongxin;Zhang, Huihui;Guo, Xiaolong;Yang, Lu;Wang, Jufang*,Elimination of carbon catabolite repression in Clostridium tyrobutyricum for enhanced butyric acid production from lignocellulosic hydrolysates,Bioresource Technology,2022
- Fu, Hongxin;Yue, Zhi;Feng, Jun;Bao, Teng;Yang, Shang-Tian;Cai, Youhua;Wang, Jufang,Consolidated bioprocessing for butyric acid production from raw cassava starch by a newly isolated Clostridium butyricum SCUT620,Industrial Crops and Products,2022